M-Audio Oxygen 49 MK IV 49-Key USB MIDI Keyboard Controller


89 out of 100. Incorporating 1650+ ratings and reviews.

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M-Audio Oxygen 49 MK IV

Gearank Recommendation

The M-Audio Oxygen 49 MK IV appeared on our recommended list for 49 Key MIDI Controller Keyboards when we published the first edition back in February 2016.


Back in January 2016 the M-Audio Oxygen 49 was the highest rated 49 key controller under $200 with a Gearank score of 88. Since that time its ratings have fallen and it's no longer on our list of recommended 49 key controllers - to see what we now recommend please read: our guide to The Best 49 Key MIDI Controller Keyboards.

The Oxygen 49 integrates with most major DAWs such as Ableton Live, Pro Tools, Logic, Cubase, and more, and it comes with transport controls.


  • Keys: 49 full size synth-action with velocity sensitivity.
  • Pads: 8 which are velocity sensitive.
  • Arpeggiator: No, but the bundled software does.
  • Motorized Controls: No.
  • Bundled Software: Ableton Live Lite, Air Xpand!2 and SONiVOX Twist virtual synths.
  • Power: USB powered.
  • Connectivity: USB and TRS input for sustain pedal.
  • Control Hardware Directly: No.
  • Compatibility: Mac OS X 10.4.11 or later (10.5 or later recommended) + Windows 10, 8, 7, Vista, and XP.
  • Dimensions: 32.04" x 9.56" x 3.7"
  • Weight 6.4 lbs


Here's a video of the Oxygen 49 MK IV in action:


Does it have a transpose

Does it have a transpose function and is it touch sensitive?

The keys are velocity

The keys are velocity sensitive but they don't have aftertouch.

It has Octave buttons which you can see in the picture above the Mod and Pitch wheels.